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年龄相关性黄斑变性的光动力疗法

http://www.cnophol.com 2008-8-15 14:29:18 中华眼科在线

Fig3 Verteporfin activated by non-themal laser

  .Treatment of ARMD with PDT-The TAP Trial,first results available in 1999

  .Verteporfin in Photodynamic therpay-The VIP Trial,first results available in 2000

  The purpose of these studies is to confirm the potential of PDT with verteporfin in the majority of patients with classic and occult CNV secondary to ARMD.

Fig4 Treated area showing CNV occlusion

  References

  1 Vinding T. Age-related macular degeneration. An epidemiological study of 1000 elderly patients. Acta Ophthalmol Scand,1995,73(Suppl.217)∶1~32

  2 Klein R,Klein B,Linton K. Prevalence of age-related maculopathy. The beaver dam eye study. Ophthalmol,1992,99∶933~942

  3 Hyman L. Epidemiology of AMD. In:Age-related macular degeneration:principles and practice. Hampton GR,Nelson PT,eds. New York:Raven Press,1992.100

  4 Bressler N. Submacular Surgery:Are randomized trials necessary? Arch Ophthalmol,1995,113∶1557~1560

  5 Klein R,Klein B,Jensen S,et al. The Five-year incidence of age-related maculopathy in the beaver dam study. Invest Ophthalmol,1996,113∶301~308

  6 Bressler N,Bressler S,Gragoudas E. Clinical characteristics of choroidal neovascular membranes. Arch Ophthalmol,1987,105∶209~213

  7 Moisseiev J,Alhalel A,Masuri R,et al. The impact of macular photocoagulation study results on the treatment of exudative age-related macular degeneration. Arch Ophthalmol,1995,113∶185~189

  8 Bressler NM,Bressler SB,Fine SL. Age-related macular degeneration. Survey Ophthalmol,1988,32∶375~413

  9 Macular Photocoagulation Study Group. Laser photocoagulation of subfoveal neovascular lesions of age-related macular degeneration. Arch Opthalmol,1993,111∶1200~1209

  10 Gragoudas ES,Schmidt-Erfuth U,Sickenberg M,et al. Results and preliminary dosimetry of photodynamic therapy for choroidal neovascularization in age-related macular degeneration in a phaseⅠ/Ⅱ study. Invest Ophthalmol Vis Sci,1997,38∶S17

  11 Schmidt-Erfuth U,Miller JW,Sickenberg M,et al. Photodynamic therapy for choroidal neovascularization in a phaseⅠ/Ⅱ study:preliminary results of multiple treatments. Invest Vis Sci Ophthalmol,1997,38∶S17

  from CIBA Vision Medical Affairs,Hong Kong

(收稿:1999-04-25,陈浩译)

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(来源:眼视光学杂志 1999年第2期第1卷 新技术介绍)(责编:zhanghui)

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