作者：Gao Y,Liang L,Tseng SC,et al.

　　出处：Cornea.2010-12;29(12):1386-91.

　　文献类型：病例 PUBMED链接：PMID: 20847679

　　Abstract：PURPOSE:To report Demodex infestation in pediatric blepharoconjunctivitis.

　　METHODS:A retro... PURPOSE:To report Demodex infestation in pediatric blepharoconjunctivitis.

　　METHODS:A retrospective review of 12 patients, with ages from 2.5-11 years, with chronic blepharoconjunctivitis who failed to respond to conventional treatments. Demodex was detected by lash sampling and microscopic examination. Patients were treated with 50% tea tree oil (TTO) eyelid scrubs or 5% TTO ointment eyelid massages for 4-6 weeks.

　　RESULTS:Demodex mites were found in all, but 1 case had cylindrical dandruff in the lashes. After 1 week of TTO treatment, all patients showed dramatic resolution of ocular irritation and inflammation while Demodex counts dropped. All corneal signs resolved within 2 weeks except for a residual anterior stromal scar in 1 eye. During a follow-up period of 8.3 ± 4.6 months, 1 patient showed recurrent inflammation, which was successfully managed by a second round of TTO treatment.

　　CONCLUSIONS:Demodicosis should be considered as a potential cause of pediatric refractory blepharoconjunctivitis. Eyelid scrubs or massage with TTO could be an effective treatment regimen in these cases.

　　中文摘要：

　　目的：报道儿科蠕形螨感染致睑结膜炎。

　　方法：回顾性分析12例慢性睑结膜炎病例，年龄2.5-11岁，常规的治疗无效，取睫毛标本进行显微镜检查发现蠕形螨虫。病人接受为期4至6周的用50%茶树油(TTO)擦拭眼睑或5%TTO软膏眼睑按摩的治疗。

　　结果：所有病例均发现有蠕形螨小虫，但只有1例发现睫毛附有圆柱形皮屑。TTO治疗1周后，全部病人眼部刺激和感染情况极大好转，而蠕形螨计数下降;2周内，除1眼角膜前基质残留瘢痕外，所有病人的角膜体征消失。在8.3±4.6月的随访中，1例病人感染复发，经TTO再次治疗后治愈。

　　结论：儿科难治性睑结膜炎病例，应考虑到蠕形螨感染的可能。TTO眼睑擦拭或按摩是有效治疗这些病例的原则。 翻译者:明亮的大眼睛

　　主题词：

　　Animals; Anti-Infective Agents, Local; Blepharitis; Child; Child, Preschool; Chronic Disease; Conjunctivitis; Eye Infections, Parasitic; Eyelashes; Female; Humans; Male; Massage; Mite Infestations; Mites; Retrospective Studies; Tea Tree Oil;

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