????????????????????????
??,??,???
????????????
???? ?? ??2%??????????????????????(PHACO)??????????????????? ?????????????38?(42?),???17?(19?),?21?(23?)??50~85(65.5�15.5)?,??????????,????2?:???20?(22?),??2??2%??????????3?/d,????????????????4?/d,????????4?/d?????????????,1?/?,??1?;???18?(20?),????????????,?????????????????1d,??1?3?7d?????????1d???1?7d????????? ?????1?3?7d???????????????,?????1?7d??????(626.21�19.57)祄?(587.93�51.88)祄;?????1?7d???????(607.91�15.83)祄?(556.07�13.00)祄,??? ?????(P<0.05)??? ??????????????????????????????????????????????
?????????/???;??????????;????
?????????????????,????????????????????????????????????????????????,?????????????????????[1]?????2%???????????????????????????????????,????????,?????????????
1 ?????
1.1 ???? 2006?1?~2007?4???????????????????????????38?(42?),???17?(19?),?21?(23?),??50~85(65.5�15.5)???????????????????2?:???18?(20?),???9?(10?),?9?(10?),??50~80(54.8�14.5)?,???20?(22?),???8?(9?),?12?(13?),??50~85(55.4�15.2)?,2?????????2???????,????????(P>0.05)?
1.2 ?? (1)??????0.5%??????????,??0.4%???????????????????+???????,?????????(OMS-OPSYS)??????????,??12�????,???3.5mm,????<40%,??100~120mmHg,?????10~30sec,??????????,??????,??????,???????????(2)?????2d?????2%??????????(??????????,????H20040951)3?/d????7d,???????,????????????????????????????????4?/d,??????4?/d???????????1?/?,????7d,??2?????????,????????
1.3 ???? ??1d??????????????,??1?3?7d????????????????(?Kelman???????[2]:0? ??????1? ???????,???????????2? ?????:?????1/8~1/6????????????3? ?????:????????????,???????????????,4???????)???1?7d??NIDEKUP1000?????????????????
1.4 ????? ??????SPSS 10.0??????,?????x�s??,??t??,?P<0.05??????????
2 ??
2.1 ????????????? 2???????,2???????????????(P>0.05),??1?
?1 2??????????? (x�s)
?? |
?? |
????(?) |
??????(祄) |
??? |
20 |
0 |
550.90�12.01 |
??? |
22 |
0 |
553.00�7.01 |
?:????,t =0.65,P>0.05
2.2 2??????????? ??1?3?7d???????????????,????????(P<0.05),??2.
2.3 2??????????? ?????????1d?7d????????????,????????(P<0.05),??3?
?2 ??????????????????? (?)
?? |
?? |
?1? |
?3? |
?7? |
0 |
1 |
2 |
3 |
4 |
0 |
1 |
2 |
3 |
4 |
0 |
1 |
2 |
3 |
4 |
??? |
20 |
3 |
10 |
7 |
0 |
0 |
5 |
11 |
4 |
0 |
0 |
13 |
4 |
3 |
0 |
0 |
??? |
22 |
5 |
12 |
5 |
0 |
0 |
9 |
10 |
3 |
0 |
0 |
19 |
2 |
1 |
0 |
0 |
?:????, P<0.05
?3 ????????????????? (x�s ,祄)
?? |
?? |
?1? |
?7? |
??? |
20 |
626.21�19.57 |
587.93�51.88 |
??? |
22 |
607.91�15.83 |
556.07�13.00 |
?:????,t =3.402,2.53,P<0.05
3 ??
????????????????????,?????????,???????????????????????????????[3],????????????????????????????,?????,????????????????????????????????,??????????????????????,??????????,??,??,???????????????,??????????,????????????????,???????????,??????????????????????????[4]????????????????????????,?????,????,?????????????????,????????????????,???????????,?????????????,???????????,???????????,????,????????,??????????????,????????[5]?????(GSH)??????????,??????????,???????????????????????????????????????,???GSHS???(GST)??????????????GSH?????(GPX)?????????????,???????????GSH??????????(GSSH),?????????,????????,?????????,??????????????????????????,???????????????,???????,??????????????????????,????????[6]??????????????????????????,??????????????????[7]??????????[2,5],???????????????????????????????????????????????????
???????1?3?7d????????????????????,?????????????,??????(P<0.05)???????????,???????????[?1?(607.91�15.83)祄 vs(626.21�19.57)祄,?7?(556.07�13.00)祄 vs (587.93�51.88)祄,P?<0.05],???????????????????????????????,??????????,?????????,???????????,???????????????,????????????????,?????????(P<0.05)?????,?????????????????????????????????????????????????????
??,????,2%??????????????????????????,?????????????????????????,???????,?????????????????????????,?????(??????????)?????
????
1 ???.????????????????????.????????,2001,19(10):765
2 Kelman C D .Phacoemulsifucation and aspiration a new technique of cataract. Am J ophthalmol,1974,64:23-25.
3 ??,???,??.???????????????????????????.?????????,2005,(03):58-59.
4 Diaz-Valle D,jose M,Sanchez BC,et al.Endothelial damage with cataract technique.J Cataract Refract Surg,1998,24:951-995.
5 ???,???.???????????????????.????????,2006,(03):263-266.
6 BjYrn Lundberg,Jonsson M,Behndig A. Postoperative corneal swelling correlates strongly to corneal endothelial cell loss after phacoemulsification cataract surgery. American Journal of Ophthalmology,2005,139(6):1035-1041.
7 ???,??,??,?.??????????????????????????????.????????(?????),2007,6:612-614 |