目的:探讨不完全型Beh et病的临床诊断要点与有效治疗方法。
方法:回顾分析52例临床确诊的不完全型Beh et病患者83只眼的临床资料,观察分析视力、裂隙灯显微镜、眼底及荧光素眼底血管造影(FFA)检查结果,着重观察分析前房或房角积脓、视盘及视网膜血管情况。所有患者均采用睫状肌麻痹剂以及全身联合应用糖皮质激素和环磷酰胺治疗,随访至少1年以上。
结果:就诊时前房或房角积脓54只眼,视盘充血41只眼。FFA检查显示所有病例均存在眼底异常改变,早期视盘血管渗漏、晚期视盘着染83只眼,占100%;弥漫性视网膜毛细血管微渗漏83只眼,占100%;受累分支血管渗漏、晚期受累血管管壁着染71只眼,占85.54%。治疗后炎症完全控制20例26只眼;控制20例33只眼;好转12例24只眼。所有患者均无前房或房角积脓,无视盘充血;至最后随访日期止未出现口腔溃疡、生殖器溃疡、关节炎病等全身表现。
结论:不完全型Beh et病多以反复发作的前房积脓、视盘炎及视网膜血管炎为主要眼部临床体征,FFA检查有助于病情诊断;早期及时应用睫状肌麻痹剂以及全身联合应用糖皮质激素和环磷酰胺治疗可有效控制病变发展。 Objective To investigate the clinical diagnosis and treatment of incomplete Beh et′s disease. Methods The clinical data of 52 patients (83 eyes ) with incomplete Beh et′s disease were retrospectively analysed. Visual acuity and results of examination of slit-lamp microscope, ocular fundus, and fundus fluorescein angiography (FFA) were observed and analysed. All of patients were treated by local cycloplegic, systemic treatment with glucocorticoid and cytoxan. The followed-up period was 1 year or more. Result |