Other Risk Factors of Pyogenic Granuloma The style of implantation surgery, the type of orbital location of HA and the low transformation efficiency of HA are risk factors of pyogenic granuloma.
The overtime operation, not strictly sterilizing of surgical instruments and accessories can also lead to chronic infection of HA implant. Under certain condition pyogenic granuloma may developed as a form of chronic infection of HA. Overweight or large size of the prosthesis, the low grade manufacture procedure of prosthesis and HA can increase the irritation and friction between implant and conjunctiva, which easily lead to implant exposure and infection. The low grade manufacture procedure and low transformation efficiency of HA cause partial vascularization of HA implant,although sufficient vascularization can prevent infection and rejection of HA. The shallower location of HA was not only difficult for installation of prosthesis, but also easy for HA implant exposure and infection.
Pyogenic conjunctival granuloma, differed with simple conjunctival granuloma, can not be controlled by medical therapy effectively, and HA implants should be removed finally. The patients suffer severe hurt. So we should emphasize the prevention of pyogenic conjunctival granuloma. Long term followup will help us monitor development of pyogenic granuloma.
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