精彩推荐:青光眼 白内障 近视 远视 散光 斜视弱视 角膜溃疡 角膜炎 沙眼 眼外伤 更多疾病
大众频道
专业频道
时尚频道
互动频道
疾 病 | 保 健 | 爱眼动态 | 名医名院
知 识 | 美 食 | 自检自测 | 爱眼纪事
资 讯 | 临 床 | 学 术 | 文 献
图 谱 | 医 患 | 继 教 | 家 园
五官之美 | 整 形 | 美 容
眼镜一族 | 妆 容 | 图 库
眼科在线 | 预留位置
眼科知道 | 在线咨询
  当前位置:当前位置: 中华眼科在线 → 医学频道 → 文献 → 正文 切换到繁體中文 用户登录 新用户注册
翼状胬肉术后90Sr β射线敷贴治疗疗效观察及复发相关因素分析

http://www.cnophol.com 2010-7-23 11:05:21 中华眼科在线

 

  There are some safety issues to be considered when using postoperative 90Sr βirradiation. First of all, the eyeball should be fixed during the radiotherapy. Eye fixation can reduce the incidence of scleral necrosis. The second safety issue is that the cornea should be protected, when the affected area is covered with the 90Sr applicator. Third, the dosage of 90Sr βirradiation and treatment time should be precise. The last but not the least, the patient should be examined everyday carefully for 10 days in order to avoid occurrence of serious side effects. If the patient has feeling of pain or chemosis, we should be extremely cautious to carry out the treatment.

  In this study, we also analyzed the factors related to local recurrence of the pterygium, after surgery and 90Sr βirradiation. The reason for high recurrence rate of pterygium in younger patients (<40 years) could be that younger persons have more opportunity to exposure to ultraviolet radiation and stronger ability of fibroblast proliferation. The healthy Bowmans membrane seems to act as a barrier to the in growth of conjunctival tissues. In patients of recurrent pterygium with previous history of surgery, the cause for recurrence could be the destruction of normal limbal structure and the changes in the tear film. There were some reports suggesting a high recurrence in males[11]. In contrast, our data didnt show statistically difference between male and female. However, our study is a retrospective analysis, and prospective studies are required to overcome the selection bias and prove this point.

  【参考文献】

  1 Ang LP, Chua JL, Tan DT. Current concepts and techniques in pterygium treatment. Curr Opin Ophthalmol 2007;18(4):308313

  2 Anduze AL, Merritt JC. Pterygium: clinical classification and management in Virgin Islands. Ann Ophthalmol 1985;17(1):9295

  3 Chen PP, Ariyasu RG, Kaza V. A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium. Am J Ophthalmol 1995;120(2):151160

  4 Panda A, Das GK, Tuli SW, Kumar A. Randomized trial of intraoperative mitomycin C in surgery for pterygium. Am J Ophthalmol 1998;125(1):5963

  5 Smith RA, Dzugan SA, Kosko P. Postoperative beta irradiation for control of pterygium. J Miss State Med Assoc 2001;42(6):167169

  6 Raiskup F, Solomon A, Landau D, Ilsar M, FruchtPery J. Mitomycin C for pterygium: long term evaluation. Br J Ophthalmol 2004; 88(11):14251428

  7 Reisman D, McFadden JW, Lu G. Loss of heterozygosity and p53 expression in pterygium. Cancer Lett 2004;206(1):7783

  8 Tan DT, Tang WY, Liu YP, Goh HS, Smith DR. Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium.

  Br J Ophthalmol 2000;84(2):212216

  9 Pajic B, Greiner RH. Long term results of nonsurgical, exclusive strontium/yttrium90 betairradiation of pterygia. Radiother Oncol 2005;74(1):2529

  10 Constable PH, Crowston JG, Occleston NL, Cordeiro MF, Khaw PT. Long term growth arrest of human Tenons fibroblasts following single applications of beta radiation. Br J Ophthalmol 1998;82(4):448452

  11 Isohashi F, Inoue T, Xing S, Eren CB,Ozeki S, Inoue T. Postoperative irradiation for pterygium: retrospective analysis of 1,253 patients from the Osaka university hospital. Strahlenther Onkol 2006;182(8):437442

  12 Mourits MP, Wyrdeman HK, JurgenliemkSchulz IM, Bidlot E. Favorable longterm results of primary pterygium removal by bare sclera extirpation followed by a single 90Strontium application. Eur J Ophthalmol 2008;18(3):327331

  13 Kirwan JF, Constable PH, Murdoch1 IE, Khaw PT. Beta irradiation: new uses for an old treatment: a review. Eye 2003;17(2):207215

  14 Kal HB, Veen RE, J rgenliemkSchulz IM. Doseeffect relationships for recurrence of keloid and pterygium after surgery and radiotherapy. Int

  J Radiat Oncol Biol Phys 2009;74(1):245251

上一页  [1] [2] 

(来源:互联网)(责编:zhanghui)

发表评论】【加入收藏】【告诉好友】【打印此文】【关闭窗口
  • 下一条信息: 没有了
  • 更多关于(90Sr,β射线敷贴治疗,翼状胬肉,复)的信息
      热门图文

    卸睫毛膏的方法

    眼袋祛除术的方法

    韩式无痕开眼角术

    内眦赘皮矫正手术
      健康新看点
      健康多视点
    ad推广
      图话健康
    点击申请点击申请点击申请点击申请点击申请
    中国眼镜网新浪福建健康21世纪药店网千龙求医查疾病整形美容英智眼科浙江眼科网中国眼网久久眼科网华夏健康网
    阿里医药眼科网首席医学网寻医问药全球医院网保健医生在线眼科中华临床医师杂志平安健康网卫生法制网视客眼镜网点击申请

    Copyright © 2007 中华眼科在线 网站备案序列号: 京ICP备08009675号
    本网站由五景药业主办 北京金鼎盛世医学传媒机构负责运营 国家医学教育发展中心提供学术支持
    服务电话:010-63330565 服务邮箱: [email protected]