摘要  
目的：观察经瞳孔温热疗法（transpupillary thermotherapy,TTT）联合球后曲安奈德注射(triamcinolone acetonide，TA)治疗脉络膜特发性新生血管（idiopathic  choroidal neovascularization， ICNV）的治疗效果。  

方法：球后注射曲安奈德使黄斑部水肿、渗出缓解后再使用法国产Iris810nm半导体激光对11例脉络膜特发性新生血管患者进行TTT治疗，采用1.0～2.0nm光斑、能量75～175mW照射时间55～60s，随诊3～4mo，通过视力，直接检眼镜检查，荧光素眼底血管造影（tundus fluorescein angiography， FFA）及吲哚青绿血管造影（indocyanine green angiography， ICGA）观察疗效。  

结果：治疗后视力提高者8例，占73%。无变化者2例18%。视力下降者1例9%。11例患者中眼底改变者10例，1例有瘢痕形成。 
 
结论：TTT+TA对脉络膜新生血管有较好的疗效，激光能量小,参数较易掌握。
  
关键词：经瞳孔温热疗法；曲安奈德；脉络膜特发性新生血管  

郑波,叶璐,孙文涛,李燕龙,王勇. 经瞳孔温热疗法联合曲安奈德球后注射治疗脉络膜特发性新生血管.国际眼科杂志,2007;7(2):571-573  

参考文献  
1 Schmidt-Erfurth U, Miller JM, Sickenberg M. Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-erlated macular degeneration: results of retreatments in aphase 1 and 2 study. Arch Ophthalmol ,1999;117:1177-1187  
2 Macular Photocoagulation Study Group .Argon laser photocoagulation for neovascular maculopathy：five-year results from randomized clinical  trias.Arch Ophthalmol ,1991;109:1109-1114  
3 Shields C, Shields J, Cater J, Lois N，Edelstein C，Gunduz K． Transpupillary thermotherapy for choroidal melanoma:tumor control and results in 100 consecutive eases . Ophthalmology ,1998;103:2142-2151  
4 Newsom RSB, Mcalister JC, Saeed M. Transpupillary thermotherapy (TTT) for the treatment of choroidal neovasculerization.Br J Ophthalmol , 2001;85:173-178
 
5王丽丽,朱忠桥,王勇,王海燕. 曲安奈德预防术后增殖性玻璃体视网膜病变临床观察.国际眼科杂志,2005;5(4):685-687  
6胡丹,惠延年,张鹏,白建伟.经瞳孔温热疗法治疗中心性渗出性脉络膜视网膜炎.中华眼底病杂志,2002;3:184-186

上一页  [1] [2]