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3展望
白内障、青光眼、眼外伤都是易致盲疾病，而先天性白内障是一种较为常见的儿童眼病，是造成儿童失明和弱视的重要原因[2225]。虽然通过及早手术有助于视力的恢复，但是由于婴幼儿视觉系统的特殊性，眼球仍在发育、屈光状态不稳定、术后炎症较重等均会增加手术的风险和难度。因此，从病因寻找治疗方法无疑是最佳选择，对先天性白内障来说很关键的晶状体蛋白组的研究为此奠定了一定的基础。但晶状体蛋白两大类家族之一的βγ家族远不如α家族研究的那样深入和广泛，而晶状体蛋白的表达以及表达模式的多样性同样增加了晶状体蛋白组的研究难度。所以，要想通过晶状体蛋白组的研究来揭示先天性白内障的发病机制，尚需进一步的深入工作。
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