6 MGD的治疗
6.1 药物治疗 根据MGD发病机理,选择相应药物治疗:①对于睑缘炎、结膜炎局部药物有红霉素、四环素、妥布霉素、全身应用四环素和四环素族药物(强力霉素等)可以改善睑板腺分泌,抑制病原菌的脂肪酶活性,从而有效控制睑缘炎和MGD。②雄性激素治疗[23]:可改善泪膜结构,对睑板腺分泌功能有促进作用。
6.2 物理治疗[24] 睑板按摩和热敷、红外线加热器或广谱加热器局部照射,促进睑板腺分泌物排出,使泪腺脂质层均匀,增加BuT,改善刺激症状。
6.3 支持治疗 包括泪小囊栓塞,口服亚油酸和亚油酸必需脂肪酸、N-乙酰半脱氨酸,达到增加泪膜稳定性的作用。
6.5 环境调节 改变生活工作习惯,缩短视频终端的使用时间,减少工作持续睁眼时间,减少泪膜蒸发[25]。
7 结语 MGD的病因多种多样,病理生理过程也十分复杂,且有多种分型,因此对此类疾病的治疗及疗效评价尚无统一标准,随着眼科学及其他边缘学科的发展,MGD越来越受到学者们的关注,将为干眼症的防治提供科学的依据。
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