¡¡¡¡Hiroshi Goto

¡¡¡¡Department of Ophthalmology Tokyo Medical University

¡¡¡¡100044

¡¡¡¡Masquerade syndrome in ophthalmology is a rare clinical entity.Representative masquerade syndromes of the eye include primary intraocular lymphoma(PIOL)and uveal metastases of extraocular tumors¡£

¡¡¡¡PIOL has 2 types of ocular manifestations£¬one is vitreous cell infiltration and the other is subretinal infiltration£¬and both mimic some sort of intraocular inflammatory disorders.Ophthalmologists should be aware of the characteristic ocular findings of PIOL£¬and proceed to conduct subsequent analysis using intraocular tissue or fluid in order to reach a definitive diagnosis¡£

¡¡¡¡Recently£¬the number of the patients with metastatic uveal tumor has been increasing in Japan.In general£¬a diagnosis of metastatic uveal tumor is not difficult to make in patients with a medical history of extraocular malignancies.However£¬patients may present with intraocular metastatic lesion first£¬without any information about extraocular malignancies.In such cases£¬analysis of intraocular tissue or fluid may contribute to a diagnosis of metastatic uveal tumor£¬as in PIOL¡£

¡¡¡¡A high degree of suspicion for intraocular malignancy is important when presented with atypical intraocular manifestations and unusual clinical courses.