【摘要】 探讨复合式小梁切除术对硅油填充术后继发性青光眼的治疗效果。方法:回顾性分析 200310/200812我院采用复合式小梁切除术,治疗硅油填充术后继发性青光眼11例11眼的手术效果。结果:患者术后达到功能性滤过泡标准比例极高。术前眼压平均为(52.3±11.5)mmHg, 术后平均眼压为(15.4±8.3)mmHg。术后平均眼压较术前明显降低,经t检验具有显著性差异,术后视力较术前提高4眼(36%),与术前视力相同5眼(45%),较术前视力略下降2眼(18%)。结论:复合式小梁切除术可以有效治疗硅油填充术后继发性青光眼。
【关键词】 复合式小梁切除术;硅油;继发性青光眼
Complex trabeculectomy in treatment of secondary glaucoma after silicone oil filling
ChaoQiong Wu, Jie Feng, PeiFeng Li, Mang Hu
Department of Ophthalmology, the First Hospital of Wuhan, Wuhan 430022, Hubei Province, China
AbstractAIM: To evaluate the effects of complex trabeculectomy in treatment of secondary glaucoma after silicone oil filling.
METHODS: Eleven cases 11 eyes with secondary glaucoma after silicone oil filling were treated with complex trabeculectomy since Oct. 2003 to Dec. 2008. Clinical observations were carried out on filtering bleb,intraocular pressure(IOP) and vision. RESULTS: High rate of functional filtering bleb formation was achieved after complex trabeculectomy. IOP was 52.3±11.5mmHg before operation and 15.4±8.3mmHg after operation,IOP was significantly dropped(P<0.01). 4 eyes (36%) had vision improved and 5 eyes (45%) had equal vision with preoperation, 2 eyes (18%) with vision decreased.CONCLUSION: Complex trabeculectomy can treat secondary glaucoma after silicone oil filling effectively.
KEYWORDS: complex trabeculectomy; silicone oil; secondary glaucoma
0引言
玻璃体切除联合眼内硅油填充是目前治疗复杂性视网膜脱离常用的手术方法。眼内硅油填充有利于提高视网膜复位率,但也可能引起诸多手术并发症,术后眼压升高就是其中之一[1]。200310/200812我院采用复合式小梁切除术,治疗保守治疗无效的硅油填充术后继发性青光眼11例11眼,取得较为满意的效果,现报告如下。
1对象和方法
1.1对象
在我院行玻璃体切除硅油填充术后3~4wk内发生高眼压的患者11 例11 眼,男7 例,女4 例, 32~57岁。其中外伤性牵引性视网膜脱离4例,孔源性视网膜脱离4 例,糖尿病增生性视网膜病变致视网膜脱离3例,术前均无青光眼病史。入院后检查视力手动4眼, 0.1者2眼,0.2~0.5者5眼,保守治疗无法控制眼压。继发性青光眼诊断标准:(1)眼压较术前增加超过10mmHg;(2)眼压超过21mmHg。手术指征:眼压超过40mmHg,经抗炎、降压药物治疗无效。
1.2方法
球后麻醉及筋膜下浸润麻醉,以下穹窿部为基底做低位结膜瓣,充分止血,在6∶00位做约4mm×3mm大小的方形巩膜瓣,深度约1/2巩膜厚度。根据个体差异采用浸透0.2mg/mL丝裂霉素C (MMC)的棉片置于巩膜瓣下及结膜瓣上切口周边部约1~2min取出后立即用约200mL平衡盐溶液反复冲洗巩膜瓣下、结膜瓣下及角膜,颞侧透明角膜作前房穿刺备用。切除约2mm×1mm角膜小梁组织及稍大于小梁切口的周边虹膜。回复巩膜瓣后采用100尼龙线间断缝合巩膜瓣两角2针,在巩膜瓣两侧切口边缘各缝合1针可拆除的外置调节缝线。经预置前房穿刺口缓缓注入平衡盐溶液恢复前房,根据房水滤过情况,调整缝线的松紧及数量,直至产生适度房水滤过。原位缝合球结膜。再次从前房穿刺口注入平衡盐溶液重建前房,并仔细检查滤过泡隆起形态、前房深度恢复情况、眼压高低及结膜瓣有无渗漏。术毕结膜下给予抗菌消炎处理。术后处理:巩膜瓣外露缝线拆除的时机:若术后前3~4d眼压在14.60~20.00mmHg,前房恢复正常,滤过泡平坦,首先行眼球按摩,按摩后滤过泡隆起或前房变浅,即应停止。若术后眼压>20.00mmHg或经滤过泡按摩无效者,在裂隙灯下先拆除1根可调节缝线并按摩,如滤过泡隆起且眼压下降,则1~2wk再拆除另1根。如先拆除1根缝线后滤过泡仍未建立,则同时拆除另1根缝线;如拆除两根外露缝线后滤过泡仍未建立(眼压>20.00mmHg) ,则行激光断线。
统计学分析:应用统计学SPSS11.0软件包对样本数行t检验,以P<0.05为有统计学意义。
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