|
5展望
安全有效的长期眼内高比重填充物是目前研究的热点。如果说重硅油在临床研究中取得了很大的可喜的成绩,尤其是对于复发性视网膜脱离，那么重硅油研究的路还很长,诸如重硅油乳化、视网膜下残留、前节毒性等问题依然有待于进一步研究。同时,绝大多数试验无论是基础还是临床研究，如果能有足够的形态学及病理学的证实,结果将更具可靠性，更有参考价值。因此，对重硅油的长期眼内填充的安全性及有效性的研究还有待于更大数据、更长时间的随访观察。
【参考文献】
1傅守静.视网膜脱离诊断治疗学.北京:科学出版社出版 1999:222246
2 Stanislao R, Federica G, Claudia B, et al. A Pilot study on the use of silicone oilRMN3 as a heavierthanwaterendotamponade agent. Graefes Arch
Clin Exp Ophthalmol 2005;243:11531157
3 Wong D, Cazabon S, Ali H, et al. Can the use of conventional silicone oil and heavy oil be a strategy for the management of proliferative vitreoretinopathy? An Acad Med Singap 2006;35:181184
4 Hillier R, Cazabon J, Wong D. The emerging role of heavy silicone oil as a tamponade agent. Eyenews 2007;1:1417
5 Wetterqvist C, Wong D, Williams R, et al. Tamponade efficiency of perfluorohexyloctane and silicone oil solutionsin a model eye chamber.
Br J Ophthalmol 2004;88:692696
6郝玉华,叶存喜.36例复发性视网膜脱离再手术分析.中国实用眼科杂志 2002;20(11):854855
7 Lappas A, Foerster AMH, Kirchhof B. Treatment of persistent macular holes with heavy silicone oil (Densiron). Invest Ophthalmol Vis Sci 2007;48:4130
8于文贞,黎晓新,姜燕荣,等.重硅油眼内填充治疗复杂视网膜脱离的临床观察.中国实用眼科杂志 2007;25(2):195197
9 Wong D, Van Meurs JC, Stappler T, et al. A pilot study on the use of perfuorohexyloctane/ silicone oil solution as a heavier than water internal tamponade agent. Br J Ophthlamol 2005;89:662667
10 Dirk S, Katrin E. First experiences with highdensity silicone oil (Densiron) as an intraocular tamponade in complex retinal detachment.
Graefes Arch Clin Exp Ophthalmol 2006;244:609619
11 Jerzy M, Bastian M, Wilfried H, et al. In vivo retinal tolerance of various heavy silicone oils. Invest Ophthalmol Vis Sci 2007;48:18731883
12 Theelen T, Tilanus M, Klevering BJ. Intraocular inflammatio following endotamponade with highdensity silicone oil. Graefes Arch Clin Exp
Ophthalmol 2004;242:617637
13 Scheer S, Boni S, Barale PO, et al. Heavy silicone oil as internal tamponade for retinal detachment: efficacy and tolerance. J Fr Ophtalmol 2006;29(2):129164 上一页 [1] [2] |
