深低温保存羊膜治疗严重睑球粘连的临床观察
何庆华，王大江，尹东芳，刘莉
作者单位：（100853）中国北京市，解放军总医院眼科
作者简介：何庆华，女，主任医师，研究方向：眼部整形及眼表疾病。
通讯作者：何庆华. [email protected]
收稿日期：2008-03-07修回日期：2008-05-05
Preserved human amniotic membrane transplantation for ocular surface reconstruction in severe symblepharon
Qing-Hua He, Da-Jiang Wang, Dong-Fang Yin, Li Liu
Department of Ophthalmology, General Hospital of Chinese PLA, Beijing 100853, China
Correspondence to: Qing-Hua He. Department of Ophthalmology, General Hospital of Chinese PLA, Beijing 100853, China. [email protected]
Received:2008-03-07Accepted:2008-05-05
Abstract
AIM: To investigate the clinical effects of preserved human amniotic membrane transplantation for ocular surface reconstruction in patients with servere symblepharon.
METHODS:Forty-three patients (46 eyes) with severe symblepharon and pseudo-pterygium were treated with symblepharon resection, and then transplanted with preserved human amniotic membrane for bulbar conjunctiva and corneal surface reconstruction.
RESULTS: During the following-up (13±3.5 months), 24 eyes obtained fine results. The ocular surface recovered with deep conjunctival fornix and free movement of eyes; 15 eyes had moderate effects, slight symblepharon recurrence but limited eye movement, which was improved compared with preoperation; 7 eyes with extensive symblepharon showed little effect.
CONCLUSION: As the treatment for severe symblepharon, preserved human amniotic membrane transplantation for ocular surface reconstruction can get better results.
KEYWORDS：amniotic membrane; ocular surface reconstruction; symblepharon
He QH, Wang DJ, Yin DF, et al. Preserved human amniotic membrane transplantation for ocular surface reconstruction in severe symblepharon. Int J Ophthalmol(Guoji Yanke Zazhi)2008;8(6):1273-1274
摘要
目的：探讨深低温保存羊膜移植治疗严重睑球粘连的临床价值。
方法：对43例46眼有严重睑球粘连及假性胬肉的患者，进行睑球粘连松解后，应用羊膜移植重建球结膜和角膜表面，观察其临床效果。
结果：在随访期内(平均13±3.5mo)，24例患者疗效为优，眼睑球粘连均得到明显改善,眼表基本恢复正常；15例疗效为良，睑球粘连部分复发,但较术前有所改善；7例因上下睑球全粘连、结膜囊闭锁愈后效果较差。
结论：对于严重的睑球粘连,深低温保存羊膜移植重建眼表是较理想的治疗方法。
关键词：羊膜；眼表重建；睑球粘连
何庆华,王大江,尹东芳,等.深低温保存羊膜治疗严重睑球粘连的临床观察.国际眼科杂志 2008;8(6):1273-1274
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