作者:修彩梅,张凤兰 作者单位:264000)中国山东省烟台市,青岛大学医学院附属烟台毓璜顶医院眼科
【摘要】 目的:体会眼睑恶性肿瘤行Mohs法切除及即期修复的手术效果
【关键词】 眼睑恶性肿瘤; Mohs法; 眼睑成形或再造
Clinical evaluation of surgical treatment for eyelid malignant tumors CaiMei Xiu, FengLan Zhang Department of Ophthalmology, Yantai Yuhuangding Hospital, Affiliated Hospital of Medical College of Qingdao University, Yantai 264000, Shandong Province, China Abstract AIM: To understand the therapeutic effect of eyelid malignant tumor excision by Mohs surgery and the reconstruction of eyelids simultaneoasly. METHODS: Thirtyfive cases underwent different management, including blepharoplasty and eyelid reconstruction according to eyelid defect simultaneoasly after eyelid malignant tumor excision by Mohs surgery.
RESULTS: All cases recovered well functionally and with good appearance. Followup lasted from 10 months to 2.5 years. 2 cases relapsed. CONCLUSION: Blepharoplasty and eyelid reconstruction have satisfied therapeutic effects after eyelid malignant tumor excision by Mohs surgery. Meibomian conjunctival flap and hard palate mucosa are applicable material for replacing tarsal plate and eyelid reconstructing.
KEYWORDS: eyelid malignant tumor; Mohs surgery; blepharoplasty and eyelid reconstruction
方法:对35例35眼眼睑恶性肿瘤行Mohs法切除后根据眼睑缺损范围及部位采用不同方法即期行眼睑成形或再造手术治疗。
结果:35例术后眼睑完整,形态及功能基本恢复正常,随访10mo~2.5a,有2例复发。
结论:眼睑恶性肿瘤行Mohs法切除后造成眼睑缺损,通过成形或再造行眼睑重建,效果满意,睑板结膜瓣或硬腭黏膜瓣是替代睑板行眼睑再造的适用材料。0引言 眼睑恶性肿瘤在眼科肿瘤中常见,目前治疗方法有手术、放疗、化疗及冷冻治疗等,但手术切除+眼睑缺损即期修复是眼睑恶性肿瘤的主要治疗方法。眼睑恶性肿瘤要求手术切除必须彻底,且造成眼睑的完全或部分缺损必须经过眼睑修复恢复眼睑的形态和功能,以保护眼球及改善容貌。我们回顾总结了200501/200810的35例眼睑恶性肿瘤切除及即期眼睑成形或再造的手术效果及临床体会,现报告如下。 1对象和方法 1.1对象 本组病例35例35眼,其中男15例,女20例。发病年龄39~82(平均61.5)岁。右眼25例,左眼10例。肿瘤位于上睑15例,其中近内眦部、近外眦部和中央部各5例,下睑20例,其中近内眦部10例,近外眦部5例,中央部5例。术后病理诊断:眼睑基底细胞癌23例,鳞状细胞癌3例,睑板腺癌5例,恶性黑色素瘤3例,Merkel瘤1例。
1.2方法
1.2.1肿瘤切除 所有病例均按Mohs法控制肿瘤切除范围,即用美蓝标记肿瘤边界,局部浸润麻醉后切除肿瘤,将超过病灶各侧约1mm宽的组织切除并标记部位,连同瘤体一同做冰冻切片病理检查,如病理报告某一边界为阳性,须再次切除相应部位组织,做冰冻切片病理检查,直到切缘阴性为止。
1.2.2整复重建眼睑 重新消毒更换洞巾器械,根据眼睑缺损范围和部位采用不同方法行眼睑成形或再造。10例为眼睑前层缺损,行邻近带蒂皮瓣或游离皮瓣修补;7例眼睑全层缺损达全长30%~50%的老年人,行直接缝合;18例眼睑全层缺损超过全长50%,不能直接缝合,采用硬腭黏膜瓣或睑板结膜瓣代替睑板,两端与残存睑板或内外眦韧带缝合,滑行皮瓣或周围皮肤带蒂皮瓣、游离皮瓣修复眼睑前层缺损。
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