青光眼             3296                                      PO0557

　　Infrared Spectroscopic Examination of Aqueous Humour

　　Jost B. Jonas MD1, David Weissbrodt,2 Ralf Mueller,2 Jessica Perrin,2 Juergen Backhaus12

　　Mannheim University of Applied Sciences, Institute for Instrumental Analysis, Mannheim, Germany, and 2Department of Ophthalmology, Faculty of Clinical Medicine Mannheim of the Ruprecht-Karls-University Heidelberg, Germany

　　Objective. To report on a new technique for examining aqueous humour.

　　Participants.  Aqueous humour samples obtained from 198 patients (cataract: n=66 eyes; age-related macular degeneration: n=66; diabetic macular edema: n=66) were in vitro examined by mid infrared spectroscopy. After training and validating the technique, 66 samples were taken for the final independent prediction.

　　Results. In computerized analysis of the spectrometric data, 22 (100%) cataract eyes were diagnosed as cataract group, 17 (77%) diabetic macular edema eyes were diagnosed as diabetic macular edema group, and 14 (64%) eyes with age-related macular degeneration were diagnosed as age-related macular degeneration group. Mid infrared spectrometry could statistically significantly (p=0.004) differentiate between the three study groups.

　　Conclusions. Mid infrared spectroscopic examination of aqueous humour may be able to differentiate eyes with cataract, age-related macular degeneration or diabetic macular edema.

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