右旋糖苷７０对干眼症患者高阶像差的影响

    贾丁,  李冰,  张立华,  王兵,  贾亚丁

    山西省眼科医院
 
    右旋糖苷70对干眼症患者高阶像差的影响
 
    [摘要]目的评价右旋糖苷70滴眼液对干眼症患者泪膜的综合影响。方法选取干眼患者25人（48眼），随机分为用药组13人，滴用右旋糖苷70眼液，对照组12人，滴用生理盐水。分别于用药前，用药后1周，1个月对受试者依次进行波前像差，BUT,Shirmer I检查。结果：用药前两组各指标均无显著差异（t=1.29,P>0.05）；用药一周后，右旋糖苷70组高阶像差下降（t=2.17,P<0.05）；用药一月后，右旋糖苷70组高阶像差明显下降（t=3.16,P<0.01）,BUT两组有显著差异(P<0.05),ShirmerI用药后一周、一月均无显著差异（P>0.05）.
结论：右旋糖苷70眼液能有效提高干眼患者泪膜稳定性和视觉质量。

    The effect of Bion Tears on tear film of dry eye

    Abstract:Aim To evaluate the effect of Bion tears on tear film of dry eye.

Methods :25 patients(48 dry eyes) were randomly divided into two groups，Treatment Group(13 patients)was dropped with Bion tears，control group (12 patients)was   dropped with 0.9%NaCl. Wavefront analysis of higher order ocular aberrations and tear break-up time(BUT)，Schirmer I test(Sit)value were measured before and after the treatment for 1 week ,1 month.

    Results:No significant differences existed between the two groups before the treatment(P>0.05).High order aberration reduced after a week(P<0.05),and reduced greatly after a month(P<0.01)in treated group.After a month ,significant differences existed in BUT values between the two groups(P<0.05).After a week and a month,Shirmer I value had no significant differences between two groups(P>0.05).

    Conclusions:Bion tears could accelerate the recovery of lacrimal film stability and improve the visual quality of dry eye.