Comparison of Optic Nerve Imaging Methods to Distinguish Normal Eyes from Those with Glaucoma 不同的视神经成像技术鉴别正常眼和青光眼的比较Michael J. Greaney, Douglas C. Hoffman, David F. Garway-Heath, Mamdouh Nakla, Anne L. Coleman and Joseph Caprioli PURPOSE. To compare the ability of qualitative assessment of optic nerve head stereophotographs (ONHPs), confocal scanning laser ophthalmoscopy (CSLO), scanning laser polarimetry (SLP), and optical coherence tomography (OCT) to distinguish normal eyes from those with early to moderate glaucomatous visual field defects.

　　目的：比较视神经乳头立体照相(ONHPs)、共聚焦激光扫描眼底镜(CSLO)、激光扫描偏振仪(SLP)、光学相干断层成像技术(OCT)对于定性鉴别正常眼和有早中期视野损坏的青光眼的视乳头的能力。METHODS. Eighty-nine eyes (63 normal, 63 age-matched with glaucoma) of 89 subjects more than 40 years of age were studied. Receiver operating characteristic (ROC) curves were generated from discriminant analysis of CSLO, SLP, and OCT measurements and from ONHP scores. Sensitivity at 80% and specificity at 90% were calculated. Differences between individual methods and combinations of methods were assessed for statistical significance. Agreement on categorization between methods () was assessed.

　　方法：89名超过40岁的研究对象中包括63只正常眼，63只年龄匹配的青光眼。分析了视神经乳头立体照相评分、共聚焦激光扫描眼底镜、激光扫描偏振仪、光学相干断层成像对青光眼诊断的ROC曲线。计算了这些检查方法在敏感性为80％，特异性为90％的取值。评价了不同检查方法之间或者联合检查方法之间的统计学差异。评价了不同方法在区分正常与非正常的一致性。

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