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  ¡¡1 Ralph GS, Binley K, Wong LF, et al. Gene therapy for neurodegenerative and ocular diseases using lentiviral vectors. Clin Sci(Lond) 2006;110(1):37ª²46

¡¡¡¡2 Poeschla EM, Wongª²Staal F, Looney DJ, et al. Efficient transduction of non dividing human cells by feline immunodeficiency virus lentiviral vectors. Nat Med 1998 ;4(3):354ª²357

¡¡¡¡3 Dull T, Zufferey R, Kelly M. A thirdª²generation lentivirus vector with a conditional packaging system. J Virol 1998;72(11):8463ª²8471

¡¡¡¡4 Sinn PL, Sauter SL, McCray PB, et al. Gene therapy progress and prospects: development of improved lentiviral and retroviral vectorsª²design, biosafety, and production. Gene Ther 2005;12(14):1089ª²1098

¡¡¡¡5 Li SF, Wei RL, Jin L. Construction and indentification of recombinant retroviral vector of apoptosis gene bclª²2. Int J Ophthalmol(Guoji Yanke Zazhi) 2006;6(4):781ª²782

¡¡¡¡6 Maddon PJ, McDougal JS, Clapham PR, et al. HIV infection does not require endocytosis of its receptor, CD4. Cell 1988;54(6):865ª²874

¡¡¡¡7 Chang LJ, Urlacher V, Iwakuma T, et al. Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system. Gene Ther 1999;6(5):715ª²728

¡¡¡¡8 Mazarakis ND. Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and accessto the nervous system after peripheral delivery. Hum Mol Genet 2001;10:2109ª²2121

¡¡¡¡9 Helseth E, Kowalski M, Gabuzda D, et al. Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants. J Virol 1990;64(5):2416ª²2420

¡¡¡¡10 Buchschacher GL,Panganiban AT.Human immunodeficiency virus vectors for inducible expression of foreign genes. J Virol 1992;66(5):2731ª²2739

¡¡¡¡11 Buchschacher GL, Wongª²Staal F. Development of lentiviral vectors for gene therapy for human diseases. Blood 2000;95(8):2499ª²2504

¡¡¡¡12 Connolly JB.Lentiviruses in gene therapy clinical research. Gene Ther 2002;9(24):1730ª²1734

¡¡¡¡13 Yu X, Zhan X, Cheng L, et al. Lentiviral vectors with two independent internal promoters transfer highª²level expression of multiple transgenes to human hematopoietic stem progenitor cells. Molecular Therapy 2003;7:827ª²838

¡¡¡¡14 Pfoiler A, Ikawa M, Dayn Y, et al. Transgenesis by lentiviral vectors£ºLack of gene silencing in mammalian embryonic stem cells and preimplantation embryos. Proc Natl Acad Sci USA 2002;99(4):2140ª²2145

¡¡¡¡15 Wang AY, Gao DW, Wang GL, et al. Construction of Tum5 gene lentiviral vector and its expression in human umbilical vein endothelial cells. Int J Ophthalmol(Guoji Yanke Zazhi) 2008;8(1):53ª²55

¡¡¡¡16 Tiscornia G, Singer O, Verma IM. Production and purification of lentiviral vectors. Nat Protoc 2006;1(1):241ª²245

¡¡¡¡17 al Yacoub N, Romanowska M, Haritonova N, et al. Optimized production and concentration of lentiviral vectors containing large inserts. J Gene Med 2007;9(7):579ª²584

¡¡¡¡18 Tschernutter M, Schlichtenbrede FC, Howe S, et al. Longª²term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirusª²mediated gene therapy. Gene Ther 2005;12(8):694ª²701

¡¡¡¡19 Segura MM, Garnier A, Durocher Y, et al. Production of lentiviral vectors by largeª²scale transient transfection of suspension cultures and affinity chromatoª² graphy purification. Biotechnol Bioeng 2007;98(4):789ª²799

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