4小结
尽管目前临床上治疗以AMD为代表的CNV相关性疾病的疗法有许多,但由于VEGF在新生血管形成中具有的关键作用,针对VEGF的抑制疗法将可能会成为一种更加科学有效的治疗途径[26-28]。作为第一种应用于眼科临床的VEGF抑制剂,临床试验的结果已初步显示出Pegaptanib治疗眼底新生血管性疾病的优越性。随着对CNV发生机制的深入研究,针对CNV病因进行的治疗将有助于保持和改善患者的视力,提高生活质量,为预防和治愈AMD及其他CNV相关疾病带来新的希望。
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