不同粘弹剂在复杂性白内障超声乳化术中的临床观察
张红言，王军
作者单位：（100730）中国北京市，首都医科大学附属北京同仁医院眼科中心
作者简介：张红言，女，主治医师，硕士研究生，研究方向：白内障。
Clinical evaluation of using different viscoelastic agent(DuoVisc and sodium hyaluronate)in complicated cataract phacoemulsification
Hong-Yan Zhang, Jun Wang
Beijing Tongren Eye Centre, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
Correspondence to: Hong-Yan Zhang. Beijing Tongren Eye Centre, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
Received:2008-03-19Accepted:2008-05-08
Abstract
AIM: To compare the abilities of Duovisc and sodium hyaluronate to protect the corneal cut and corneal endothelium during endocapsular complicated cataract phacoemulsification and intraocular lens implantation.
METHODS: 106 cases (106 eyes) with complicated cataract undergone endocapsular phacoemulsification with intraocular lens (IOL) implantation were randomly divided into 2 groups, Duovisc group (53 eyes) and sodium hyaluronate group (53 eyes) as control. The amount of the cornea endothelial cell were measured before and after operation.
RESULTS: There were no statistically significant differences between two groups in age, phacoemulsi-fication time and energy during operation (P>0.05). There was statistically significant differences when compared the amount of the cornea endothelial cell in the sodium hyaluronate group before and 1 day, 1 month after surgery (P<0.01) . While there was no significant differences of those in Duovisc group before and after 1 day, 1 month surgery. (P>0.05).
CONCLUSION: Duovisc and sodium hyaluronate comparable in their ability to protect the corneal endothelium during complicated cataract phacoemulsi-fication, the results suggest that the Duovisc better than sodium hyaluronate to protect corneal endothelial cell.
KEYWORDS:complicatedcataract;sodiumhyaluronate;phacoemulsification
Zhang HY, Wang J. Clinical evaluation of using different viscoe-lastic agent (DuoVisc and sodium hyaluronate) in complicated cataract phacoemulsification. Int J Opthalmol(Guoji Yanke Zazhi)2008;8(6):1167-1169
摘要
目的：比较两种粘弹性物质DuoVisc和透明质酸钠（其胜）在复杂性白内障超声乳化术中对角膜切口水肿及角膜内皮的影响。
方法：将复杂性白内障（抗青光眼术后小瞳孔、陈旧性虹膜炎瞳孔后粘连）106眼，随机分成2组，其中透明质酸钠A组（其胜）53眼；其中抗青光眼术后小瞳孔21眼、陈旧性虹膜炎瞳孔后粘连32眼。DuoVisc组B组53眼；其中抗青光眼术后小瞳孔23眼、陈旧性虹膜炎瞳孔后粘连30眼。两组患者在白内障术前均有青光眼病史（且均有抗青光眼手术史）和陈旧性虹膜炎史。部分患者曾行两次以上抗青光眼手术，所有患者无糖尿病等全身疾病史。采用超声乳化白内障摘除联合折叠人工晶状体植入术，术前术后采用非接触式角膜内皮镜（NONCON ROBO SP60000）于术前、术后1wk和术后1，3mo对角膜内皮细胞进行随访观察，并对中央区0.25mm×0.37mm范围内进行计数密度测量。
结果：两组一般情况包括年龄、超声能量与时间的乘积无显著性差异（P>0.05）；两组术前测量角膜内皮数无显著性差异（P>0.05）；术后1d，1wk角膜水肿的患者B组明显轻于A组（P<0.01）；当角膜水肿为（++~+++）时、角膜内皮损伤、丢失的修复在术后1wk，1mo内B组明显优于A组（P<0.01）；术后3mo 2组比较差异无显著性（P>0.05）。
结论：在复杂性白内障超声乳化术中使用粘弹剂DuoVisc对减少角膜术后水肿及对角膜内皮细胞的保护明显优于透明质酸钠（其胜）。
关键词：小瞳孔白内障；粘弹剂；超声乳化术
张红言，王军.不同粘弹剂在复杂性白内障超声乳化术中的临床观察.国际眼科杂志2008;8(6):1167-1169 |
