14 BckerMeffert S, Rosenstiel P, Rhl C, et al. Erythropoietin and VEGF promote neural outgrowth from retinal explants in postnatal rats. Invest Ophthalmol Vis Sci 2002;43(6):20212026
15 Fu QL,Wu W,Wang H, et al. Upregulated endogenous erythropoietin/erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension. Cell Mol Neurobiol 2008;28(2):317329
16 Brines ML, Ghezzi P, Keenan S, et al. Erythropoietin crosses the blood brain barrier to protect against experimental brain injury. Proc Natl Acad Sci USA 2000;12;97(19):1052610531
17 Wang HY, Niu YJ, Wang PS, et al. Erythropoietin administration protects retina against lightinduced retinal degeneration. Zhonghua Yan Ke Za Zhi 2005;41(5):434438
18 Guo Y, WangWH. The protective function of erythropoietin to the ratretina after acute intraocular hypertension. Int J Ophtahlmol(GuojiYanke Zazhi) 2007;7(3):688 691
19周爱儒,查锡良.生物化学.(第6版).北京:人民卫生出版社 2005:347348
20 Chong ZZ, Lin SH, Kang JQ, et al. Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3 and 8. J Neurosci Res 2003;71(5):659669
21 Chong ZZ, Kang JQ, Maiese K. Apaf1, BclxL, cytochrome c, and caspase9 form the critical elements for cerebral vascular protection by erythropoietin. J Cereb Blood Flow Metab 2003;23(3):320330
22 Zhang F, Wang S, Cao G, et al. Signal transducers and activators of transcription 5 contributes to erythropoietinmediated neuroprotection against hippocampal neuronal death after transient global cerebral ischemia. Neurobiol Dis 2007;25(1):4553
23 Digicaylioglu M,Lipton SA.Erythropoietinmediated neuroprotection involves crosstalk between Jak2 and NFkappaB signaling cascades. Nature 2001;412(6847):641647
24 Siebenlist U. Signal transduction: barriers come down. Nature 2001;412(6847):601602
25 Maiese K, Li F, Chong ZZ. Erythropoietin in the brain: can the promise to protect be fulfilled? Trends Pharmacol Sci 2004;25(11):577583
26 Villa P, Bigini P, Mennini T, et al. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J Exp Med 2003;198(6):971975
27 Klingmüller U, Lorenz U, Cantley LC, et al. Specific recruitment of SHPTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 1995;80(5):729738
28 Kilic U, Kilic E, Soliz J, et al. Erythropoietin protects from axotomyinduced degeneration of retinal ganglion cells by activating ERK1/2. FASEB J 2005;19(2):249251
29 Weishaupt JH,Rohde G, Plking E, et al. Effect of Erythropoietin Axotomy Induced Apoptosis in Rat Retinal Ganglion Cells. Invest Ophthalmol Vis Sci 2004;45(5):15141522
30 Sttler MB, Merkler D, Maier K, et al. Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Cell Death Differ 2004;11(Suppl 2):S181192
31 Chong ZZ, Li F, Maiese K. Erythropoietin requires NFkappaB and its nuclear translocation to prevent early and late apoptotic neuronal injury during betaamyloid toxicity. Curr Neurovasc Res 2005;2(5):387399
32 Kretz A, Happold CJ, Marticke JK, et al. Erythropoietin promotes regeneration of adult CNS neurons via Jak2/Stat3 and PI3K/AKT pathway activation. Mol Cell Neurosci 2005;29(4):569579
33 Sakanaka M, Wen TC, Matsuda S, et al. In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc Natl Acad Sci USA 1998;95(8):46354640
34 Agnello D, Bigini P, Villa P, et al. Erythropoietin exerts an antiinflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res 2002;952(1):128134
35 Savino C, Pedotti R, Baggi F, et al. Delayed administration of erythropoietin and its nonerythropoietic derivatives ameliorates chronic murine autoimmune encephalomyelitis. J Neuroimmunol 2006;172(12):2737
36 Erbayraktar S, Grasso G, Sfacteria A, et al. Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo. Proc Natl Acad Sci USA 2003;100(11):67416746
37 Mennini T, De Paola M, Bigini P, et al. Nonhematopoietic erythropoietin derivatives prevent motoneuron degeneration in vitro and in vivo. Mol Med 2006;12(78):153160
38 Gil JM, Leist M, Popovic N, et al. Asialoerythropoetin is not effective in the R6/2 line of Huntingtons disease mice. BMC Neurosci 2004;5:17
39 Junk AK, Mammis A, Savitz SI, et al. Erythropoietin administration protects retinal neurons from acute ischemia reperfusion injury. Proc Natl Acad Sci USA 2002;99(16):1065910664
40 LaVail MM, Battelle BA. Influence of eye pigmentation and light deprivation on inherited retinal dystrophy in the rat. Exp Eye Res 1975;21(2):167192
41 Stockmann C, Fandrey J. Hypoxiainduced erythropoietin production: a paradigm for oxygenregulated gene expression. Clin Exp Pharmacol Physiol 2006;33(10):968979
42 Grimm C, Wenzel A, Groszer M, et al. HIF1induced erythropoietin in the hypoxic retina protects against lightinduced retinal degeneration. Nat Med 2002;8(7):718724
43 Zhong Y, Yao H, Deng L, et al. Promotion of neurite outgrowth and protective effect of erythropoietin on the retinal neurons of rats. Graefes Arch Clin Exp Ophthalmol 2007;245(12):18591867
44 King CE, Rodger J, Bartlett C, et al. Erythropoietin is both neuroprotective and neuroregenerative following optic nerve transection. Exp Neurol 2007;205(1):4855
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