Frequency of Spontaneous Pulsations of the Central Retinal Vein in Glaucoma

　　Jost B.Jonas Ulrich Legler

　　Frequency of Spontaneous Pulsations of the Central Retinal Vein in Glaucoma 100005

　　Purpose:To assess the prevalence of spontaneous pulsations of the central retinal vein in eyes with chronic open-angle glaucoma versus normal eyes in the setting of a general ophthalmic practice.

　　Method:The clinical observational case-series study included 167 eyes of subjects with chronic open-angle glaucoma and 704 eyes of subjects of a control group.The optic disc was ophthalmoscopically assessed using a non-contact ophthalmoscopic lens at the slit lamp in medical mydriasis.

　　Results:pontaneous pulsations of the central retinal vein were observed in significantly(P=0.005;OR：0.59;95%CI：0.41，0.84)less eyes of the glaucoma group(64.1±3.7%%)than in the eyes of the control group(75.3±1.6%).In both groups，the presence of a spontaneous central retinal vein pulsation was statistically(P>0.10)independent of age，gender，refractive error and intraocular pressure.

　　Conclusions:Confirming hospital-based studies，the results suggest that assessment of the central retinal vessel pulsations as part of a dynamic optic disc examination may clinically be useful for the diagnosis of glaucoma.