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血管内皮生长因子及其受体与眼底新生血管

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35 Nguyen QD, Shah SM, Hafiz G. A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration. Ophthalmology ,2006;113(9):1522.e1-1522.e14

36 Singh N, Amin S, Richter E, Rashid S, Scoglietti V, Jani PD, Wang J, Kaur R, Ambati J, Dong Z, Ambati BK. Flt-1 Intraceptors Inhibit Hypoxia-Induced VEGF Expression In Vitro and Corneal Neovascularization In Vivo .Invest Ophthalmol Vis Sci ,2005;46:1647-1652

37 Ideno J, Mizukami H, Kakehashi A. Prevention of diabetic retinopathy by intraocular soluble flt-1 gene transfer in a spontaneously diabetic rat model. Int J Mol Med ,2007;19(1):75-79

38 VEGF Inhibition Study in Ocular Neovascularization (V.I.S.I.O.N.) Clinical Trial Group; D'Amico DJ, Masonson HN, Patel M, Adamis AP, Cunningham ET Jr, Guyer DR, Katz B. Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials. Ophthalmology ,2006;113(6):992-1001

39 Adamis AP, Altaweel M, Bressler NM, Cunningham ET Jr, Davis MD, Goldbaum M, Gonzales C, Guyer DR, Barrett K, Patel M; Macugen Diabetic Retinopathy Study Group. Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals. Ophthalmology ,2006;113(1):23-28

40 Robinson GS, Pierce EA, Rook SL, Foley E, Webb R, Smith LE. Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy.Proc Natl Acad Sci USA , 1996;93(10):4851-4856

41 Lai CM, Spilsbury K, Brankov M, Zaknich T, Rakoczy PE. Inhibition of corneal neovascularization by recombinant adenovirus mediated antisense VEGF RNA.Exp Eye Res ,2002;75(6):625-634

42 曹晖,许迅,樊莹,王方,张皙.反义VEGF对视网膜新生血管的干预研究.眼科研究 , 2004;22:256-259

43 Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.Mol Vis , 2003,9:210-216

44 Shen J, Samul R, Silva RL. Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1. Gene Ther ,2006,13(3):225-234

45 Kim SH, Jeong JH, Lee SH, Kim SW, Park TG. PEG conjugated VEGF siRNA for anti-angiogenic gene therapy. J Controlled Release ,2006;116(2):123-129

46 蔡春梅,孙葆忱,刘旭阳.短发夹RNA 对人视网膜色素上皮细胞VEGF表达的抑制.中华眼科杂志 , 2006;42(4):334-337

47 Cashman SM, Bowman L, Christofferson J. Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD. Invest Ophthalmol Vis Sci , 2006;47(8):3496-3504

48 Takahashi H, Obata R, Tamaki Y. A novel vascular endothelial growth factor receptor 2 inhibitor, SU11248, suppresses choroidal neovascularization in vivo. J Ocul Pharmacol Ther , 2006;22(4):213-218

49 Konopatskaya O, Churchill AJ, Harper SJ. VEGF165b, an endogenous C-terminal splice variant of VEGF, inhibits retinal neovascularization in mice. 2006;12:626-632

50 许建华,刘哲丽,李若溪,孔伟,张巍.曲安奈德对缺氧条件下恒河猴脉络膜视网膜内皮细胞VEGF表达的影响.国际眼科杂志 , 2006;6(5):1053-1055

51 Kim YH, Chung IY, Choi MY, Kim YS, Lee JH, Park CH, Kang SS, Roh GS, Choi WS,Yoo JM, Cho GJ. Triamcinolone suppresses retinal vascular pathology via a potent interruption of proinflammatory signal-regulated activation of VEGF during a relative hypoxia. Neurobiol Dis , 2007;26(3):569-576

52 Wilkinson-berka JL, Jones D, Taylor G. SB-267268, a nonpeptidic antagonist of alpha(v)beta3 and alpha(v)beta5 integrins, reduces angiogenesis and VEGF expression in a mouse model of retinopathy of prematurity. Invest Ophthalmol Vis Sci , 2006;47(4):1600-1605

53 Neu J, Afzal A, Pan H. The dipeptide Arg-Gln inhibits retinal neovascularization in the mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci , 2006;47(7):3151-3155

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