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氧化应激与糖尿病视网膜病变

http://www.cnophol.com 2009-4-8 10:49:39 中华眼科在线

14 Obrosova IG, Pacher P, Szabo C, et al. Aldose reductase inhibition counteracts oxidativenitrosative stress and poly(ADPribose)polymerase activation in tissue sites for diabetes complications. Diabetes 2005;54(1):234242

15 Mohamed AK, Bierhaus A, Schiekofer S, et al. The role of oxidative stress and NFκB activation in late diabetic complications. Biofactors 1999;10:157167

16 Kowluru RA. Effect of advanced glycation end products on accelerated apoptosis of retinal capillary cells under in vitro conditions. Life Sci 2005;76(9):10511060

17 Wu Y, Wu G, Qi X, et al. Protein kinase C beta inhibitor LY333531 attenuates intercellular adhesion molecule1 and monocyte chemotactic protein1 expression in the kidney in diabetic rats. J Pharmacol Sci 2006;101(4):335343

18 Ohshiro Y, Ma RC, Yasuda Y, et al. Reduction of diabetesinduced oxidative stress,fibrotic cytokine expression,and renal dysfuntion in protein kinase Cβnull mice. Diabetes 2006;55(11):31123120

19 Kaneto H, Xu G, Song KH, et al. Activation of the hexosamine pathway leads to deterioration of pancreatic βcell function through the induction of oxidative stress. J Biol Chem 2001;276(33):3109931104

20 Li H, Hu Z. Role of vascular endothelial growth factor in the progress of diabetic retinopathy. Int J Ophthalmol(Guoji Yanke Zazhi) 2008;8(5):990 993

21樊小娟,张小玲.糖尿病视网膜病变发病机制中VEGF与PEDF的研究进展.国际眼科杂志2007;7(2):485 488

22 Lu M, Kuroki M, Amano S, et al. Advanced glycation end products increase retinal vascular endothelial growth factor expression. J Clin Invest 1998;101(6):12191224

23 Fan XJ, Zhang XL. Perspectives on VEGF and PEDF in the pathogenesis of diabetic retinopathy. Int J Ophthalmol(Guoji Yanke Zazhi) 2007;7(2):485 488

24 Amano S, Yamagishi S, Inagaki Y, et al. Pigment epitheliumderived factor inhibits oxidative stressinduced apoptosis and dysfunction of cultured retinal pericytes. Micrevsac Res 2005;69(1 2):4555

25 Wang SF,Ren B,Gao XW.Research progress of PEDF. Int J Ophthalmol(Guoji Yanke Zazhi) 2007;7(4):11161118

26 DeBosch BJ, Baur E, Deo BK, et al. Effects of insulinlike growth factor1 on retinal endothelial cell glucose transport and proliferation. J Neurochem 2001;77(4):11571167

27 Kowluru RA, Koppolu P, Chakrabarti S, et al. Diabetesinduced activation of nuclear transcriptional factor in the retina,and its inhibition by antioxidants. Free Radical Res 2003;37(11):11691180

28 Kowluru RA, Koppolu P. Diabetesinduced activation of caspase3 in retina:effect of antioxidant therapy. Free Radical Res 2002;36(9):993 999

29 FeitLeichman RA, Kinouchi R, Takeda M, et al. Vascular damage in a mouse model of diabetic retinopathy:relation to neuronal and glial changes. Invest Ophthalmol Vis Sci 2005;46(11):4281 4287

30 Podesta F, Romeo G, Liu WH, et al. Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro. Am J Pathol 2000;156(3):10251032

31 Kowluru RA, Kowluru V, Xiong Y, et al. Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetesinduced oxidative stress. Free Radical Biol Med 2006;41(8):11911196

32 Kowluru RA, Abbas SN. Diabetesinduced mitochondrial dysfunction in the retina. Invest Ophthalmol Vis Sci 2003;44(12):5327 5334

33 Kowluru RA, Odenbach S. Effect of longterm administration of αlipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats. Diabetes 2004;53(12):32333238

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