作者:罗谦,程依琏,杨 影 作者单位:(610041)中国四川省成都市,四川省医学科学院 四川省人民医院眼科
【摘要】 目的:分析青光眼睫状体炎综合征临床表现,发病原因及诊断治疗方法。方法:对我院200101/200810临床诊断为青光眼睫状体炎综合征患者32例进行追踪和回顾性分析。结果:32例病例中首诊误诊的有5例。随访时间4~8(平均6)a,长期观察表明:该综合征每年发作次数不等,差别较大,因人而异,每次发作无明确诱因,多次反复发作,大多数视功能不受影响,本组病例中仅4例患者经反复发作后药物控制不佳,出现了视野及视盘改变,进行了外滤过手术治疗,效果较好。结论:青光眼睫状体炎综合征临床表现为单眼复发性睫状体炎伴眼压升高,大多反复发作,但多数不出现视野及视盘改变。在临床上该病易被误诊,必须掌握其诊断与鉴别诊断的要点。应长期观察视野及视盘变化情况,避免造成视功能持续损害。
【关键词】 青光眼睫状体炎综合征;原因;诊断;治疗
作者简介:罗谦,女,学士,副主任医师,研究方向:青光眼。
Clinical analysis of PosnerSchlossmans syndrome on 32 cases
Qian Luo, YiLian Cheng, Ying Yang
Department of Ophthalmology,Sichuan Academy of Medical Sciences & Sichuan Provincial Peoples Hospital,Chengdu 610041, Sichuan Province,China
Abstract
AIM: To analyze the clinic manifestation, pathologenic reason, and the diagnosis and treatment methods of PosnerSchlossmans syndrome(PSS).
METHODS: We respectively analyzed for 32 patients of PSS from January 2001 to October 2008.
RESULTS: There are five patients for misdiagnosis ,the following time is 48 years, the average time is 6 years, the observing indicate that the times of outbreak of this syndrome varied every year, having obvious difference, according to different person, having not obvious inducement, repeat outbreak, not influencing to the visual function mostly, 4 patients can not be controlled by medicine after repeat outbreak , having changes of visual field and optic disc, after trabeculectomy operation, having good effect.
CONCLUSION: PSS manifest with high IOP, cyclitis, repeat outbreak, having not changes of visual field and optic disc. It is easy to misdiagnose in clinic, so must master the points of diagnosis and differentiation. So we should observe the changes of visual field and optic disc, preventing damage the visual function continuously.
KEYWORDS:PosnerSchlossmans syndrome; cause; diagnosis; treatment
0引言
青光眼睫状体炎综合征(glaucomato cyclitic syndrome)简称青睫综合征,1948年由Posner和Schlossman首次报告,故又称PosnerSchlossman综合征。该病多见于20~50岁的中青年人,儿童和60岁以上的人发病极少。多为单眼发病,或双眼交替发病,很少同时累及双眼。发病机制尚不明确。以往认为该病是一种自限性疾病,虽有反复发作的特点,但最终对视功能无影响,近年来的研究发现,如果眼压持续升高而药物难以控制时同样可以导致视野丢失、杯/盘比扩大等不可逆性视功能损害。现将我院门诊200101/200810诊断,治疗32例青睫综合征患者分析报告如下。
1对象和方法
1.1对象 选择200101/200810在我院门诊确诊的青睫综合征患者32例,单眼发病28例,双眼发病4例。其中双眼同时发病4例,交替发作3例。男21例,女11例,年龄18~56(平均32±14.2)岁。首诊误诊的有5例。临床表现:本组患者29例发作时无自觉症状或仅有轻度不适,视物模糊或虹视,有3例有轻度睫状体充血,并伴有同侧头痛,眼胀痛。所有患者发作时均有不同程度视力下降,眼压恢复后,视力恢复正常,角膜均有不同程度的角膜后沉着物(keratic precipitate,KP),呈灰白色、小圆形、羊脂状,多位于角膜下方,有2例伴有角膜轻度水肿。前房深浅均正常,瞳孔正常或稍大,对光反射正常或稍迟钝。不发生虹膜后粘连或周边前粘连。眼压:所有患者发作时眼压均升高38~60mmHg。眼压升高时前房角开放,眼底视盘均正常,仅有4例反复发作多年后药物不能控制,出现视野缺损和杯/盘比扩大,后行外滤过手术后得以控制。随访4~8(平均6)a。本组32例患者均有反复发作病史,每次发作均无明确诱因,发作时间持续2~7d者14例,8~14d者16例,有2例延续1mo。每年发作数次,也有1~2a发作1~2次,因人而异,差异较大。有4例患者反复发作后药物不能控制眼压,出现了视野及视盘的改变,故进行了外滤过手术治疗。
[1] [2] 下一页 |